Endocrine Abstracts

Introduction: The aim of our experimental study was to investigate the effect of both T2DM and metformin treatment on myocardial tolerance to ischemia-reperfusion injury and cardiac AMP-activated protein kinase (AMPK) activity.Methods: The protocol included four groups: i) controls (n=13) – non-diabetic rats treated with i.p. vehicle injections for 3 days prior to the heart perfusion, ii) controls+metformin (CM; n=12) – non-diabet...

Introduction: Gestational diabetes mellitus (GDM) is a common complication of pregnancy. Identification of early determinants of GDM is necesary to designate possible preventive strategies. The aim of this study was to reveal the most significant risk factors for GDM.Design: A total of 209 women with singleton pregnancies were included in the study. Maternal fasting glucose, anthropometric parameters and blood pressure were measured in the first trimeste...